Laboratory of Biological Oxidation







Selected Publications
Monographs:

Khatisashvili, G., Gordeziani, M., Varazi, T., Kurashvili, M., Pruidze, M. Oxigenases of Biomembranes (Physiology and Biochemistry). Tbilisi, 2009

Gordeziani M., Khatisashvili, G. Chemical Modification of Cytochrome P450. Tbilisi, 2008 [Full text (PDF)]

Gordeziani M., Varazi T., Kurashvili M., Pruidze M. Biological Oxidation and Chemiosmosis. Tbilisi, 2007

Kvesitadze, G., Khatisashvili, G., Sadunishvili, T., Ramsden, J.J. Biochemical Mechanisms of Detoxification in Higher Plants: Basis of Phytoremediation. Berlin, Heidelberg, Springer, 2006 [Limited versin ]

Papunidze, V., Khatisashvili, G., Sadunishvili, T. Plant for a Healthy Environment. Batumi, Ajara, 2005

Gordeziani, M., Khatisashvili, G. Membranous Xenobiochemistry. Tbilisi, 2005

Kvesitadze, G., Khatisashvili, G., Sadunishvili, T., Evstigneeva, Z. Metabolism of Anthropogenic Toxicants in Higher Plants. Moscow, Nauka, 2005

Gordeziani, M., Khatisashvili, G., Kirtadze, E. Bioenergetic and Regulation of Oxidative Processes. Tbilisi, 2004

Gordeziani, M., Kvesitadze G. Chemical Basis of Ecology. Tbilisi, 2000

Articles:

Khatisashvili G.,Sulamanidze L., Amasukeli N., Adamia G., Kurashvili M., Kuprava N., Kirtadze E. Selection of Microorganisms for Remediation of Soils Polluted With Explosives. International Conference: "The Main Problems of Ecological Microbiology and Biotechnology". November 24-25, 2009, Baku, Azerbaijan, 239-246

Varazi T., Khatisashvili G., Amiranashvili L., Pruidze M., Varsimashvili Kh., Adamia G., Kvaratskhelia M. Bioremediation of Soils Polluted With Oil Hydrocarbons. International Conference: "The Main Problems of Ecological Microbiology and Biotechnology". November 24-25, 2009, Baku, Azerbaijan,109-112

Varazi T., Gagelidze N.,  Gordeziani M., Pruidze M., Ananiashvili T.,  Sachaneli T., Kvaratskhelia M. Modeling of Bioutilization Process of Paraffin and Naphthenic Hydrocarbons (Wax). International Conference: "The Main Problems of Ecological Microbiology and Biotechnology". November 24-25, 2009, Baku, Azerbaijan, 113-117

Gordeziani, M., Khatisashvili, G., Gagelidze, N., Sulamanidze, L., Kvesitadze, E. Plants and Microorganisms for Rehabilitation of Ecosystems Polluted With Explosives. 5th IGBF: “International Greek Biotechnology Forum”; Athens, Greece, May, 8-10, 2009

Khatisashvili, G., Pruidze, M., Adamia, G., Bandzeladze, S., Kipiani, A., Chubinidze, A. The Induction of Peroxidase and Phenoloxidase in Plant Leaves by Systemic Pesticides. Annals of Agrarian Sciences, 2009, 7, 4, 63-65

Khatisashvili, G., Gordeziani, M., Adamia, G., Kvesitadze, E., Sadunishvili T., Kvesitadze. G. Higher Plants Ability to Assimilate Explosives. WCSET 2009: "World Congress on Science, Engineering and Technology"; Amsterdam, The Netherlands, September, 2009

Kurashvili, M., Gordeziani, M., Varazi, T., Ananiashvili, T., Kordzadze, N., Chubinidze, A. The Iinfluence of Systemic Fungicides in vivo of Functioning of Some Oxides of Plants. Annals of Agrarian Science. 2009, 7, 2, 53–56 [Full text (PDF)]

Kvesitadze, G., Khatisashvili, G., Sadunishvili, T., Gagelidze N., Kharebashvili M.,  Ramsden J.J. On the strategy of ecological guarantee of oil pipelines. 10th International UFZ-Deltares/TNO Conference on Soil-Water Systems in cooperation with Provincia di Milano. ConSoil 2008, Milano, Italy, 3-6 June, 2008

Khatisashvili, G., Pruidze, M., Adamia, G., Papunidze, V. Role of vegetable ferments in ambient cleaning. Plant and Microbial Enzymes: isolation, characterization and biotechnology applications. Tbilisi, Georgia, 2-5th July, 2007, 42–46

Kurashvili, M., Varazi, T., Ananiashvili, T., Gordeziani, M. Participation of plant oxidizing enzymes in hydroxylation of the hydrocarbons. Plant and Microbial Enzymes: isolation, characterization and biotechnology applications. Tbilisi, Georgia, 2-5th July, 2007, 60–63

Adamia, G., Ghoghoberidze, M., Graves, D., Khatisashvili, G., Kvesitadze, G., Lomidze, E., Ugrekhelidze, D., Zaalishvili, G. Absorption, distribution and transformation of TNT in higher plants. Ecotoxicology and Environmental Safety. 2006, 64, 136–145 [Abstract] [Full text (PDF)]

Kurashvili, M., Ananiashvili, T., Kiskeidze, E. Chemical modification of  monooxygenase system during xenobiotic oxidation. Annals of Agrarian Science. 2006, 4, 1, 29–33

Pruidze, M.V., Khatisashvili, G.A., Omiadze, N.T. Oxidation of organic xenobiotics by phenoloxidase from tea leaves. Annals of Agrarian Science. 2006, 4, 2, 69–72

Gogava, M., Ramishvili, M., Gogoberidze, M., Kurashvili, M., Pruidze, M., Chelidze, N. TNT effect on nitroreductase, peroxidase and phenoloxidase activities in vitro cultures of Yucca gloriosa and Glycine max. Proceedings of the Georgian Academy of Sciences, Biological Series B. 2006

Adamia, G., Varazashvili, T., Ananiashvili, T., Kurashvili, M., Pruidze, M., Gvakharia, V., Machitadze, N., Gordeziani, M. Study of Lead Accumulation Ability of some Sowing Plants. Bulletin of the Georgian Academy of Sciences. 2005, 171, 3, 592–595

Best, E.P.H., Kvesitadze, G., Khatisashvili, G., Sadunishvili, T. Plant processes important for the transformation and degradation of explosives contaminants. Zeitschrift für Naturforschung. 2005, 60c, 340–348 [Abstract] [Full text (PDF)]

Varazashvili, T., Pruidze, M. Uptake and oxidative degradation of pentane in plants. Journal of Biological Physics and Chemistry. 2005, 5, 4, 145–150 [Abstract] [Full text (PDF)]

Zaalishvili, G., Varazashvili, T., Ananiashvili, T., Khatisashvili, G., Kvesitadze E. Ultrastructural Reorganization of plant cell in the process of xenobiotics metabolism. Annals of Agrarian Science. 2005,  3, 3, 117122

G. Khatisashvili, G. Adamia, N. Gagelidze, L. Sulamanidze, D. Ugrekhelidze and M. Ghoghoberidze,Elaboration of methods of bioremediation of contaminated soils on former military locations and proving grounds in Georgia. European Symposium of Environmental Biotechnology – ESEB 2004, Oostende (Belgium), April 25-28, 2004

Khatisashvili, G., Kvesitadze, G., Adamia, G., Gagelidze, N., Sulamanidze, L., Ugrekhelidze, D., Zaalishvili, G., Ghoghoberidze, M., Ramishvili, M. Bioremediation of contaminated soils on the former military locations and proving grounds in Georgia. Journal of Biological Physics and Chemistry. 2004, 4, 3, 162–168 [Abstract] [Full text (PDF)]

Kvesitadze, G., Best, E.P.H., Khatisashvili, G., Sadunishvili, T. Plant process important for the transformation and degradation of explosives contaminants. In: Phytoremediation: environmental and molecular biological aspects. OECD workshop, Hungary, Abstracts, 2004, 55

G. Kvesitadze, G. Khatisashvili, T. Sadunishvili. Mechanisms to Detoxify Selected Organic Contaminants in Higher Plants and Microbes, and Their Potential Use in Landscape Management. Letter report. Contract number 62558-04-P-6107. European Research Office, U.S. Army Engineer Research and Development Center, United Kingdom, 2004, 144 pages.

Tinikashvili, L., Varsimashvili, K., Gagelidze, N., Amiranashvili, L., Chrikishvili, D., Kirtadze, E., Khatisashvili, G., Ghoghoberidze, M. Influence of temperature on growth and degradation ability of microorganisms capable for degradation of 2,4,6-trinitrotoluene and mineral oil. Proceedings of the Georgian Academy of Sciences, Biological Series A. 2004, 30, 4, 493497

Varsimashvili, Kh., Tinikashvili, L., Amiranashvili, L., Gagelidze, N., Kirtadze, E., Khatisashvili, G., Ghoghoberidze, M. Influence of some physicochemical factors in different microorganisms capable for degradation of 2,4,6-trinitrotoluene and mineral oil. Proceedings of the Georgian Academy of Sciences, Biological Series B. 2004, 2, 3-4, 104109

Khatisashvili, G., Adamia, G., Pruidze, M., Kurashvili, M., Varazashvili, T., Ananiashvili, T. TNT uptake and nitroreductase activity of plants. 8th International FZK/TNO Conference on Contaminated Soil. ConSoil 2003, Gent, Belgium, 2-16 May, 2003, 2482–2485

Kiskeidze, E., Zaalishvili, G., Ebelashvili, M., Khatisashvili, G., Kurashvili, M., Gordeziani, M. Changes of plant monooxygenase system during xenobiotic oxidation. Proceedings of the Georgian Academy of Sciences, Biological Series A. 2003, 29, 5-6, 639–644

Kuchukashvili, Z., Davitaia, G., Gorozia, I., Kvesitadze, G., Lomidze E., Khatisashvili G. Antioxidant characteristics of phenolic compounds of Satureia hortensis. Journal of Biological Physics and Chemistry. 2003, 3, 3/4. 85–88 [Abstract] [Full text (PDF)]

Kurashvili, M., Pruidze, M., Kiskeidze, E., Varazashvili, T., Ananiashvili, T., Khatisashvili, G., Gordeziani, M. Influence of different factors on nitrobenzene oxidation in the plant cell. Journal of Biological Physics and Chemistry. 2003, 3, 2, 4549 [Abstract] [Full text (PDF)]

Kuchukashvili, Z., Davitaia, G., Avaliani, N., Lomidze, E., Khatisashvili, G., Arziani, B. The influence of prostaglandins on oxidative metabolism of 3,4-benzpyrene in rat liver cell microsomes. Bulletin of the Georgian Academy of Sciences. 2003, 168, 1, 101–104

Adamia, G., Khatisashvili, G., Varazashvili, T., Ananiashvili, T., Gvakharia, V., Adamia, T., Gordeziani M. Determination of the type and rate of soil contamination with heavy metals and organic toxicants on the territories of military proving grounds in Georgia. Bulletin of the Georgian Academy of Sciences. 2003, 167, 1, 155158

Khatisashvili, G., Gordeziani, M., Varazashvili, T., Pruidze, M. The role of oxidative enzyme systems in the process of phytoremediation. Contaminated Soils, Sediments and Water. London, UK. 2001, August 14–17

Kvesitadze, G., Gordeziani, M., Khatisashvili, G., Sadunishvili, T., Ramsden, J.J. Some aspects of the enzymatic basis of phytoremediation. Journal of Biological Physics and Chemistry. 2001, 1, 2, 4957 [Abstract] [Full text (PDF)]

Varazashvili, T., Kurashvili, M., Pruidze, M., Gordeziani, M. Monooxygenase system participation in the processes of plant adaptation. Proceedings of the Georgian Academy of Sciences, Biological Series A. 2001, 27, 33–37

Varazashvili T., Khatisashvili G., Kurashvili M., Pruidze M., Ananiashvili T.,  Zaalishvili G., Gordeziani M. Nitrobenzene oxidizing enzymes in plant cells. Journal of Biological Physics and Chemistry. 2001, 1, 85–88 [Abstract] [Full text (PDF)]

Varazashvili, T., Zaalishvili, G., Kurashvili, M., Pruidze, M., Gordeziani, M. Participation of the plant monooxygenase system in adaptation to environmental stress. Journal of Biological Physics and Chemistry. 2001, 1, 38–42 [Abstract] [Full text (PDF)]

Gogoberidze, M., Zaalishvili, G., Khatisashvili, G., Ugrekhelidze, D., Gordeziani, M., Kvesitadze, G. Bioremediation – contemporary strategy of xenobiotics’ detoxification. Contaminated Soil 2000 (Proceedings of the 7th International FZK/TNO Conference). 2000, 1, 397–404

Korte, F., Kvesitadze, G., Ugrekhelidze, D., Gordeziani, M., Khatisashvili, G., Buadze, O., Zaalishvili, G., Coulston, F. Review: Organic toxicants and plants. Ecotoxicology and Environmental Safety. 2000, 47, 1, 1–26 [Abstract]

Mchedlishvili, N., Pruidze, M., Omiadze, N., Pruidze, G. Selection of plant raw materials for obtaining the food red color and study of its pigments stability. Bulletin of the Georgia Academy of Sciences. 2000, 162, 2, 367–368 ]

Kiskeidze, E., Khatisashvili, G., Kurashvili, M., Shavgulidze, G. Action of lipid peroxidation on monooxygenase System participating in xenobiotic detoxification. Bulletin of the Georgian Academy of Sciences. 2000, 162, 1,156158

Zaalishvili, G., Ebelashvili, M., Varazashvili, T., Pruidze, M., Sadunishvili, T. Influence of nitrobenzene different concentrations on maize root tip cells ultrastructure results. Biotechnology 2000.  Health Care Agriculture and Food Environmental Biotechnology. ICC-Berlin, 2000, 3–8 September

Mchedlishvili, N., Pruidze, M., Omiadze, N., Pruidze, G., Gulua, L. The investigation of coloring substances of Phytolacca americana by means to their use in food industry. The Problems of Agrarian Science. Scientific Works. X. 2000, 153–157

Varazashvili, T., Kurashvili, M., Pruidze, M., Gordeziani, M. About participation of monooxygenase system in the processes of plant adaptation. The Problems of Agrarian Science. Scientific Works. IX, 2000, 110–111

Kiskeidze, E., Khatisashvili, G., Gordeziani, M. Changes of plant monooxygenase system while xenobiotics oxidation. The Problems of Agrarian Science. Scientific Works. IX, 2000, 115–118

Ananiashvili, T., Khatisashvili, G., Gordeziani, M. About energetic significance of initial components of plant monooxygenase system. The Problems of Agrarian Science. Scientific Works. IX, 2000, 119–123

Zaalishvili, G., Khatisashvili, G., Ugrekhelidze D., Gordeziani, M., Kvesitadze G. Plant potential for detoxification (Review). Applied Biochemistry and Microbiology. 2000, 36, 5, 443–451 [Abstract]

Gordeziani, M., Khatisashvili, G., Ananiashvili, T., Varazashvili, T., Kurashvili, M., Kvesitadze, G., Tkhelidze, P. Energetic significance of plant monooxygenase individual components participating in xenobiotic degradation. International Biodeterioration and Biodegradation. 1999, 44, 49–54 [Abstract]

Mchedlishvli, N., Pruidze, G., Pruidze, M., Omiadze, N. Influence of the phenols on betacianine systems. Proceedings of International Scientific Conference. Kazakhstan, Almaty, 1999

Khatisashvili, G., Gordeziani, M., Kvesitadze, G., Korte, F. Plant monooxygenases: participation in xenobiotic oxidation. Ecotoxicology and Environmental Safety. 1997, 36, 118–122 [Abstract] [Full text (PDF)]

Pruidze, G., Jincharadze, M., Varazashvili, T., Omiadze, N. Peptides of black tea dry concentrate and their amino acid composition. Bulletin of the Georgian Academy of Sciences. 1996, 154, 3, 448–449

Khatisashvili, G., Kurashvili, M., Gordeziani, M. Isolation of plant microsomal fraction and characterization of its oxidative systems. Bulletin of the Georgian Academy of Sciences. 1995, 152, 818–824

Khatisashvili, G., Kurashvili, M., Gordeziani, M., Kvesitadze, G. Functional evolution of separate components of plant monooxygenase system involved in xenobiotic detoxication. Fresenius Environmental Bulletin. 1994, 3, 621–626

Khatisashvili, G., Kurashvili, M., Gordeziani, M., Kvesitadze, G. Monooxygenase and peroxydase pathways of xenobiotics detoxication in higher plants. Fresenius Environmental Bulletin. 1993, 2, 103–108

Khatisashvili, G., Kurashvili, M., Chkhikvishvili, I., Gordeziani, M., Kvesitadze, G. Transformation of monooxygenase mechanism into peroxidase one and microsomal oxidation of flavonoids in plants. Proceedings of the Georgian Academy of Sciences, Biological Series. 1993, 19, 318–323

Balashvili, M., Gordeziani, M., Khatisashvili, G., Papelishvili, R., Jokhadze, D. Removal of xenobiotic inhibitory effect by acceleration of their hydroxylation of protein and RNA-synthesizing activity in plants. Proceedings of the Georgian Academy of Sciences, Biological Series. 1992, 18, 5, 303–310

Khatisashvili, G., Gordeziani, M. Hydroxylation of xenobiotics by plant cytochrom P-450. Proceedings of VII International Conference: "Biochemistry and Biophysics of Cytochrome P-450; Structure and Function, Biotechnological and Ecological Aspects". Moscow, Russia, 1991, 546–548

Gordeziani, M., Khatisashvili, G., Kvesitadze, G. Free and coupled with hydroxylation of xenobiotics oxidation of NADPH.  Doklady AN SSSR. 1991, 320, 2, 417–420

Gordeziani, M., Khatisashvili, G., Kurashvili, M. Distribution of NADPH-cytochrome P-450-reductase in plant cell. Bulletin of the Georgian Academy of Sciences. 1991, 143, 321–324

Khatisashvili, G., Gordeziani, M., Kurashvili, M. Cytochromal components of plant microsomes and possibility of their induction. Bulletin of the Georgian Academy of Sciences. 1991, 143, 183–192

Tkhelidze, P., Ananiashvili, T., Khachidze, O. Transformation of 14С-sucrose in grapes shoots and bunches. Bulletin of the Georgian Academy of Sciences. 1989, 135, 2, 433–436

Togonidze, L., Khatisashvili, G., Kobakhidze, L., Gordeziani, M. NAD(P)H-Dependent fractional oxidation of dimethylaniline in plant leaves. Bulletin of the Georgian Academy of Sciences. 1990, 140, 125–128

Khatisashvili, G., Gordeziani M., Lomidze, E., Adamia, G. NADPH redox-cycle at oxygen deficite in cell-free plant systems. Abstracts of V International Conference: “Cytochrome P-450 and Modification of Macromolecules”. Ukraine, Yalta,  1989, 156

Gordeziani, M., Khatisashvili, G., Adamia, G. The cytochrome P450-containing monooxygenase system of plant membranes. Works of VI International Conference: “Biological Membranes in Norm and Pathology”. Georgia, Tbilisi, 1989,  41–43

Gordeziani, M. Cytochrome P450 in plants. Proceedings of the Georgian Academy of Sciences, Biological Series. 1987, 13, 3, 177–186

Gordeziani, M., Khatisashvili, G., Adamia, G., Lomidze, E. The capacity of cytochrome P450 to switch transferring from “endogenous“ to “exogenous” regimeof metabolism. Bulletin of the Georgian Academy of Sciences. 1987, 126, 1, 161–164 

Gordeziani, G., Durmishidze, S., Khatisashvili, G., Adamia, G., Lomidze, E. Investigation of biosynthesic and detoxificational ability of plant cytochrome P450. Doklady AN SSSR. 1987, 295, 6, 1491–1493

Gordeziani, G., Khatisashvili, G., Adamia, G., Kurashvili, L. Investigation of some functions of Cytochrome P-450 of plant microsomes. Proceedings of IV International Conference: “Cytochrome P-450 and Environmental Protection”. Russia, Novosibirsk, 1987, 51–52

Khatisashvili, G., Adamia, G., Gordeziani, M., Lomidze, E., Brisker, V. Polarographic studies of plant microsome hydroxylation ability. Bulletin of the Georgian Academy of Sciences. 1986, 123, 3, 621–623

Gordeziani, M., Durmishidze S., Bobokhidze, E., Lomidze, E. Involvement of mitochondrial and microsomal oxidative systems in detoxication of xenobiotics with leaves. Fiziologia Rastenii (Moscow). 1982, 29, 5, 978–984

Patents:

Amiranashvili, L., Gagelidze, N., Tinikashvili, L., Khatisashvili, G., Gogoberidze, M., Kvesitadze. G. Method of cleaning of soils contaminated with crude oil and oil products. License for utility model. Georgian Patent GE U 2004 1128 U

 

 

 

 

 

 

 

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